FIRST AMENDMENT TO
THIS AMENDMENT by and between BIOGEN IDEC INC., (the Company), and Cecil B. Pickett (the
Executive), dated as of October 28, 2008.
WHEREAS, the Executive and the Company are parties to an Employment Agreement dated as of June
21, 2006 (the June 21, 2006 Agreement); and
WHEREAS, the Executive and the Company desire to amend the June 21, 2006 Agreement as set
NOW, THEREFORE, it is hereby agreed as follows:
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